Efficacy of a novel herbal formulation for weight loss demonstrated in a 16‐week randomized, double‐blind, placebo‐controlled clinical trial with healthy overweight adults
| Autor: | Dinesh Venkata Kamath, Kashinath Dixit, Krishnaraju Venkata Alluri, Barbara A. Davis |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Waist Endocrinology Diabetes and Metabolism 030204 cardiovascular system & hematology Overweight Placebo Placebos Young Adult 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology Double-Blind Method Weight loss Internal medicine Weight Loss Weight management Internal Medicine medicine Humans 030109 nutrition & dietetics business.industry Cholesterol Body Weight Middle Aged Clinical trial Treatment Outcome chemistry Health Female Anti-Obesity Agents Plant Preparations medicine.symptom business Body mass index Phytotherapy |
| Zdroj: | Diabetes, Obesity and Metabolism. 20:2633-2641 |
| ISSN: | 1463-1326 1462-8902 |
| DOI: | 10.1111/dom.13443 |
| Popis: | AIM To re-evaluate the weight loss efficacy of LI85008F in healthy overweight adults via a 16-week randomized, double-blind, placebo-controlled clinical study. MATERIALS AND METHODS One hundred and forty overweight participants (body mass index [BMI] 27-29.9 kg/m2 , 29.3% male; ages 21-50 years) were randomized into placebo (n =70) and LI85008F (n =70) groups. The participants received either 900 mg/d of LI85008F in two divided doses or two identical placebo capsules. In addition, participants were counselled to follow an ~1800 kcal/d diet and to engage in walking for 30 min, 5 d/wk throughout the study. RESULTS At the end of the trial period, the LI85008F supplemented group showed significant reductions in body weight (5.36 ± 1.769 vs. 0.87 ± 1.381 kg; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text