Contribution and Acceptability of Bacteriological Collection Tools in the Diagnosis of Tuberculosis in Children Infected with HIV
| Autor: | Sahoura Fatimata Nacro, Makoura Barro, Saga Alain Ouermi, Philippe Msellati, Boubacar Nacro, Pegdewende Eliane Kiema, Bintou Sanogo |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Tuberculosis HIV Infections Sensitivity and Specificity 03 medical and health sciences 0302 clinical medicine Nasopharyngeal aspirate 030225 pediatrics Internal medicine Burkina Faso medicine Humans Sampling (medicine) 030212 general & internal medicine Prospective Studies Adverse effect Prospective cohort study Child Tuberculosis Pulmonary business.industry Sputum Mycobacterium tuberculosis medicine.disease Infectious Diseases Tolerability Pediatrics Perinatology and Child Health Vomiting Female medicine.symptom business |
| Zdroj: | Journal of tropical pediatrics. 67(2) |
| ISSN: | 1465-3664 |
| Popis: | Objective The objective of this study is to evaluate the feasibility and tolerability of new bacteriological samples to diagnose tuberculosis (TB) in HIV-infected children. Method and patients HIV1-infected children with suspicion of TB in Universitary Hospital Sourô Sanon (Burkina Faso) were included in a prospective cohort study. Children underwent three gastric aspirates (GA) if aged Results Sixty-three patients were included. Mean age was 8.92 years, 52.38% were females. Ninety-five GA, 67 sputum, 62 NPA, 60 stool and 55 ST had been performed. During sampling, the main adverse events were cough at 68/95 GA and 48/62 NPA; sneeze at 50/95 GA and 38/62 NPA and vomiting at 4/55 ST. On the behavioral scale, the average pain score during collection was 6.38/10 for GA; 7.70/10 for NPA and 1.03/10 for ST. Of the 31 cases of TB, bacteriological confirmation was made in 12 patients. Conclusion ST, stool is well-tolerated alternatives specimens for diagnosing TB in children. NPA has a poor feasibility and tolerability in children. |
| Databáze: | OpenAIRE |
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