Preparation of stimuli-responsive nanogels based on poly(N,N-diethylaminoethyl methacrylate) by a simple 'surfactant-free' methodology
| Autor: | Angel Licea-Claverie, Lizbeth A. Manzanares-Guevara, Francisco Paraguay-Delgado |
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| Rok vydání: | 2017 |
| Předmět: |
Materials science
Surfactant free Stimuli responsive technology industry and agriculture Diethylaminoethyl Methacrylate Emulsion polymerization macromolecular substances 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics Methacrylate 01 natural sciences 0104 chemical sciences Colloidal gold Polymer chemistry General Materials Science 0210 nano-technology Nanogel |
| DOI: | 10.6084/m9.figshare.5552644 |
| Popis: | The synthesis of poly(N,N-diethylaminoethyl methacrylate)-core-polyethyleneglycol-shell (PDEAEM-core-PEG-shell) nanogels was achieved by using a “surfactant-free” emulsion polymerization with the aid of commercially available polyethyleneglycol methyl ether methacrylates (PEGMAs) as polymerizable stabilizers. By adjusting the synthetic parameters like the choice of initiator, cross-linker, PEGMA:DEAEM ratio, and molecular weight of PEGMA, a series of core-shell nanogels varying in size (50–350 nm), PDEAEM content, and pH/temperature responsive behavior were obtained in reactions taking only 60 min. The nanogels were used as nanoreactors for the preparation of gold nanoparticles. The PEGylated nanogels have a great potential to be used for diagnosis and therapy. |
| Databáze: | OpenAIRE |
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