Seroprevalence of transfusion transmitted infections in healthy blood donors: A 5-year Tertiary Care Hospital experience
| Autor: | Heena M Desai, Gaythri P Amonkar, Gururaj V Puranik, Sushama A Chandekar, Nitin Valvi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
hepatitis C virus
Pediatrics medicine.medical_specialty HBsAg Hepatitis B virus Blood transfusion Hepatitis C virus medicine.medical_treatment lcsh:Medicine 030204 cardiovascular system & hematology medicine.disease_cause 03 medical and health sciences 0302 clinical medicine medicine Seroprevalence transfusion transmitted infections human immunodeficiency virus seroprevalence business.industry Transmission (medicine) lcsh:R Retrospective cohort study medicine.disease Syphilis Original Article business 030215 immunology |
| Zdroj: | Journal of Laboratory Physicians Journal of Laboratory Physicians, Vol 9, Iss 04, Pp 283-287 (2017) |
| ISSN: | 0974-7826 0974-2727 |
| Popis: | INTRODUCTION: Transfusion transmitted infections (TTIs) can cause threat to bloody safety as blood transfusion is an important mode of transmission of TTI to the recipient, hence, to prevent transmission of these diseases, screening tests on blood bags is an important step for blood safety. AIM: This study was undertaken with the aim of determining the seroprevalence of TTI in healthy blood donors in a tertiary care blood bank. MATERIALS AND METHODS: A retrospective study was carried out over a period of 5 years from January 2007 to December 2011. Serum samples were screened for hepatitis B surface antigen (HBsAg), antibodies to human immunodeficiency virus (HIV) Type 1 and 2, hepatitis c virus (HCV) and syphilis using enzyme-linked immunosorbent assays with the third generation kits and venereal disease research laboratory test, respectively. RESULTS: A total of 76,653 healthy donors were included out of which majority of donors were male (91.79%). The overall seroprevalence of HIV, HBsAg, HCV, and syphilis were 0.26%, 1.30%, 0.25%, and 0.28%, respectively. CONCLUSION: Methods to ensure a safety blood supply should be encouraged. For that, screening with a better selection of donors and use of sensitive screening tests including nucleic acid testing technology should be implemented. |
| Databáze: | OpenAIRE |
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