Porphyria As A Problem In Anaesthesia
Autor: | F. F. Lepinskie |
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Rok vydání: | 1963 |
Předmět: |
medicine.medical_specialty
business.industry Mortality rate Disease medicine.disease Porphyrias chemistry.chemical_compound Anesthesiology and Pain Medicine Porphyria chemistry Respiratory failure Anesthesiology Metabolic disturbance Anesthesia Porphobilinogen medicine Humans Intensive care medicine business Contraindication |
Zdroj: | Canadian Anaesthetists’ Society Journal. 10:286-296 |
ISSN: | 0008-2856 |
DOI: | 10.1007/bf03001957 |
Popis: | Porphyria represents a basic metabolic disturbance and appears in many forms. Two of these, both acute, are of importance to the anaesthesiologist. It is a difficult disease to recognize because it can simulate so many other abdominal emergencies. When confronted with these emergencies, only an awareness of the disease and a knowledge of its intricacies will suggest the possibility that this condition is present and lead to testing of the urine for porphobilinogen. The future treatment of the disease may hold a large role for the anaesthesiologist. Severe neurological involvement with respiratory failure may soon be treated in the respiratory unit and then, perhaps, the high mortality rate can be lowered. Dundee2 feels that this disease is possibly the only single absolute contraindication to using thiopentone as an induction agent. All other anaesthetic agents, with the possible exception of neostigmine and regional techniques, may be employed. |
Databáze: | OpenAIRE |
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