Renal cell carcinoma in functional renal graft: Toward ablative treatments
| Autor: | Xavier Tillou, Arnaud Doerfler, S. Collon, K. Guleryuz |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Ablation Techniques
medicine.medical_specialty medicine.medical_treatment 030232 urology & nephrology Cryotherapy 030230 surgery 03 medical and health sciences 0302 clinical medicine Renal cell carcinoma medicine Carcinoma Humans Carcinoma Renal Cell Kidney transplantation Dialysis Transplantation business.industry Cancer medicine.disease Kidney Transplantation Kidney Neoplasms Surgery surgical procedures operative Clear cell carcinoma business Tumor Graft |
| Zdroj: | Transplantation Reviews. 30:20-26 |
| ISSN: | 0955-470X |
| Popis: | The occurrence of a kidney transplant tumor is a rare but serious issue with a double risk: the return to dialysis and the development of metastatic cancer. Publications on this topic are mainly case reports. The purpose of this review was to report an exhaustive literature review of functional graft renal cell carcinomas to highlight the impact of tumors on the renal graft outcomes. 201 de novo renal carcinomas in functional renal grafts from 69 publications were included. Incidence was estimated at 0.18%. Graft tumors were mostly asymptomatic (85.9%). Whatever the discovery circumstances of graft tumors, they were mostly documented by graft ultrasounds supplemented by CT-scanning or MR imaging. Nephron sparing surgery (95 patients) was the first treatment performed followed by radiofrequency ablation (38 patients) and cryotherapy (10 patients). The most common tumor graft histology was clear cell carcinoma (46.4%), followed by papillary carcinoma (43.7%). Specific mortality was 2.9% with 6 deaths. Renal graft cell carcinoma is a rare pathology with a low specific death. When possible, conservative treatment should be the first choice. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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