Molecular Basis for Chemical Evolution of Flavones to Flavonols and Anthocyanins in Land Plants
| Autor: | Rong Ni, Chun-Jing Sun, Ping-Ping Wang, Ai-Xia Cheng, Chang-Jun Liu, Ting-Ting Zhu, Piao-Yi Wang, Xiao-Shuang Zhang, Dan-Dan Li, Hong-Xiang Lou |
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| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
Flavonols Physiology Physcomitrella Physcomitrium Plant Science Genes Plant 01 natural sciences Flavones Anthocyanins Evolution Molecular chemistry.chemical_compound Selaginella moellendorffii Gene Expression Regulation Plant Dioxygenase Botany Genetics Research Articles chemistry.chemical_classification Evolution Chemical biology biology.organism_classification chemistry Embryophyta Adaptation Flavanone 010606 plant biology & botany |
| Zdroj: | Plant Physiol |
| ISSN: | 1532-2548 0032-0889 |
| DOI: | 10.1104/pp.20.01185 |
| Popis: | During the course of evolution of land plants, different classes of flavonoids, including flavonols and anthocyanins, sequentially emerged, facilitating adaptation to the harsh terrestrial environment. Flavanone 3β-hydroxylase (F3H), an enzyme functioning in flavonol and anthocyanin biosynthesis and a member of the 2-oxoglutarate-dependent dioxygenase (2-ODD) family, catalyzes the hydroxylation of (2S)-flavanones to dihydroflavonols, but its origin and evolution remain elusive. Here, we demonstrate that functional flavone synthase Is (FNS Is) are widely distributed in the primitive land plants liverworts and evolutionarily connected to seed plant F3Hs. We identified and characterized a set of 2-ODD enzymes from several liverwort species and plants in various evolutionary clades of the plant kingdom. The bifunctional enzyme FNS I/F2H emerged in liverworts, and FNS I/F3H evolved in Physcomitrium (Physcomitrella) patens and Selaginella moellendorffii, suggesting that they represent the functional transition forms between canonical FNS Is and F3Hs. The functional transition from FNS Is to F3Hs provides a molecular basis for the chemical evolution of flavones to flavonols and anthocyanins, which contributes to the acquisition of a broader spectrum of flavonoids in seed plants and facilitates their adaptation to the terrestrial ecosystem. |
| Databáze: | OpenAIRE |
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