Prevalence and pattern of cardiac autonomic dysfunction in newly detected type 2 diabetes mellitus
| Autor: | Abhay Sahoo, Viveka P Jyotsna, Kishore Kumar Deepak, Vishnubhatla Sreenivas |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Autonomic function medicine.medical_specialty Endocrinology Diabetes and Metabolism Diaphragmatic breathing Endocrinology Diabetic Neuropathies Heart Rate Diabetes mellitus Internal medicine Heart rate Internal Medicine medicine Humans business.industry Cold pressor test Type 2 Diabetes Mellitus Heart rate variation Heart General Medicine Middle Aged medicine.disease Autonomic Nervous System Diseases Diabetes Mellitus Type 2 Heart innervation Cardiology business |
| Zdroj: | Diabetes Research and Clinical Practice. 83:83-88 |
| ISSN: | 0168-8227 |
| Popis: | Cardiac autonomic functions were assessed in 145 consecutive recently detected type 2 diabetics. Ninety-nine healthy persons served as controls. Criteria for normalcy were, heart rate variation during deep breathingor=15 beats/min, deep breathing expiratory to inspiratory R-R ratioor=1.21, Valsalva ratioor=1.21, sustained handgrip testor=16 mm of mercury, cold pressor testor=10, BP response to standingor=10mm of mercury and 30:15 R-R ratio on standingor=1.04. An abnormal test was defined as the above parameters being10 beats/min,1.21,1.21,or=10mm of mercury,10,or=30 mm of mercury andor=1.0, respectively. A borderline test was defined as, heart rate variation during deep breathing 11-14, sustained handgrip test 11-15 mm of mercury, BP response to standing 11-29 mm of mercury and 30:15 R-R ratio on standing 1.01-1.03. Parasympathetic dysfunction was found in 44.2% and sympathetic dysfunction in 51.9% diabetics. Among healthy controls, these figures were 11.9% and 22.1%, respectively. Cardiac autonomic function was normal in 7.8% patients and 32.5% healthy controls. |
| Databáze: | OpenAIRE |
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