The Role of Chromoendoscopy in the Surveillance of the Duodenum of Patients with Familial Adenomatous Polyposis
| Autor: | Rosangela Filiberti, Sabrina Blanchi, Massimo Conio, Massimo Picasso |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Physiology medicine.medical_treatment Indigo Carmine Gastroenterology Chromoendoscopy Familial adenomatous polyposis Duodenal Neoplasms Internal medicine medicine Periampullary cancer Humans In patient Coloring Agents Duodenoscopy neoplasms Colectomy medicine.diagnostic_test business.industry Hepatology medicine.disease people.cause_of_death digestive system diseases Endoscopy medicine.anatomical_structure Adenomatous Polyposis Coli Duodenum Female business people |
| Zdroj: | Digestive Diseases and Sciences. 52:1906-1909 |
| ISSN: | 1573-2568 0163-2116 |
| DOI: | 10.1007/s10620-006-9653-8 |
| Popis: | Adenomas of the duodenum have been described in patients with familial adenomatous polyposis (FAP). Patients with FAP are at high risk for the development of periampullary cancer. The aim of our study was to evaluate if endoscopic visualization of small polyps, often overlooked at standard endoscopic examination, was improved by chromoendoscopy. Ten patients with FAP and previous colectomy underwent upper gastrointestinal endoscopy. Two skilled endoscopists were involved for each endoscopy. Evaluation of number and diameter of polyps was made before and after staining. After staining we detected a larger number of duodenal polyps than found at the standard endoscopic examination, the difference being statistically significant. This result seems to suggest that chromoendoscopy may improve diagnostic yield of endoscopy. Further studies are needed to suggest the best surveillance program and the appropriate therapeutic modality for these patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink