Herbal Transformation by Fermentation
| Autor: | Eun-Su Jang, Samkeun Lee, In-Kyu Choi, Kee-Jung Bang, Chang-Gue Son |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0211 other engineering and technologies
02 engineering and technology 03 medical and health sciences 0302 clinical medicine Lactobacillus Cell Line Tumor 021105 building & construction Humans Radix Volume concentration Biotransformation Chromatography High Pressure Liquid biology Traditional medicine Cynanchum Chemistry food and beverages lcsh:Other systems of medicine General Medicine cynanchi atrati Radix lcsh:RZ201-999 biology.organism_classification 030205 complementary & alternative medicine Transformation (genetics) herbal Anesthesiology and Pain Medicine Complementary and alternative medicine Melanoma cell line Fermentation sense organs Drugs Chinese Herbal |
| Zdroj: | Journal of Acupuncture & Meridian Studies, Vol 13, Iss 5, Pp 167-168 (2020) |
| ISSN: | 2093-8152 |
| Popis: | We herein show a dramatic change of herbal properties of the composition as well as function via fermentation of Cynanchi atrati Radix (family Asclepiadaceae). Cynanchi atrati Radix showed a high cytotoxicity against B16-F10 melanoma cell line, but the function of Cynanchi atrati Radix was completely changed into anti-melanin activity at very low concentration after Lactobacillus -fermentation. In addition, the compounds were drastically changed as shown in HPLC-based profile. Furthermore, this transformation has been achieved by only Lactobacillus -fermentation. This study proposes an strategy which we need to consider in the herb-derived material researches including pharmacopuncture. |
| Databáze: | OpenAIRE |
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