From the DNA Gyrase Inhibitor Cyclothialidine to a New Class of Antibacterial Agents

Autor:	Raffaello Masciadri, Peter Angehrn, Helmut Link, Hans Gmuender, Erwin Goetschi, Peter Reindl, Fabienne Ricklin, Thomas Luebbers, Paul Hebeisen, Dirk Kostrewa, Frank-Peter Theil
Rok vydání:	2003
Předmět:	Natural products biology medicine.drug_class Chemistry Antibiotics Cyclothialidine General Medicine General Chemistry DNA gyrase Biochemistry Enzyme inhibitor medicine biology.protein Antibacterials Dna gyrase inhibitor QD1-999
Zdroj:	CHIMIA, Vol 57, Iss 4 (2003)
ISSN:	2673-2424 0009-4293
Popis:	Cyclothialidine (Ro 09-1437) is a potent DNA gyrase inhibitor that was isolated from S. filipinensis NR0484. In this account we describe the identification of potent antibacterials structurally derived from this virtually neat enzyme inhibitor.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cbd862f03328de297d6204aa61590e https://doi.org/10.2533/000942903777679505 Zobrazit plný text záznamu