Ondokuz Mayıs Üniversitesi’nde 2 yıllık süreçte baş boyun kitlelerinde ince iğne aspirasyon biyopsisi deneyimimiz -50 vaka

Autor: Cem Bayraktar, Ilkser Akpolat, Sinan Atmaca, Senem Çengel, Ahmet Aksoy
Rok vydání: 2012
Předmět:
Zdroj: Volume: 29, Issue: 2 131-133
Journal of Experimental and Clinical Medicine
ISSN: 1309-5129
1309-4483
DOI: 10.5835/jecm.omu.29.02.010
Popis: Bu calismada bas ve boyun kitlelerinde ince igne aspirasyon biyopsilerini histopatolojik sonuclar ile karsilastirip, diagnostik olarak sensitivite ve spesifitesini saptamayi hedefliyoruz. Agustos 2008-Temmuz 2010 tarihleri arasinda klinigimize bas boyun bolgesinde yerlesik kitle yakinmasi ile basvuran ve cerrahi eksizyon oncesi Ince Igne Aspirasyon Biyopsisi (IIAB) uygulanan 50 hasta retrospektif olarak incelendi. Arastirma kapsamina alinan 50 hastanin 26’si (% 52) erkek, 24’u (% 48) kadindi. Ortalama yas: 54,3±17,8 ve median yas: 55 (18 yas-84 yas) idi. Histopatolojik olarak malign etiyoloji saptanan 29 (% 58) hastanin; 10’unda (% 34,4) IIAB tanisi “malignite pozitif”, 4 hastada (% 13,7) “malignite negatif” ve 15 hastada (% 51,7) ise “kategorize edilemeyen “ ve/veya “degerlendirme icin yetersiz” olarak raporlandi. Yirmi bir hastada (% 42) benign histopatolojik sonuc elde edilmekle birlikte, bu hastalarin hicbirinde malignite yonunden pozitif IIAB sonucu izlenmedi. On iki hastada (% 57,1) “malignite negatif” sonuc bulunurken, 9 hastada (% 42,8) “kategorize edilemeyen” ve/veya “degerlendirme icin yetersiz” olarak saptandi. IIAB ile tani konabilen malign etiyolojilerden en sik yassi hucreli kanser, benign etiyolojilerden ise nonspesifik inflamasyon izlendi. IIAB’in duyarliligi % 71,4, spesifitesi % 100 ve dogrululuk orani ise % 84,6 olarak bulundu. Literatur ile karsilastirildiginda dusuk duzeyde duyarlilik ve dogruluk oranlari saptanmasi; IIAB degerlendirilmesinde yeterince yetkinlesilememesinden, biyopsilerin farkli kisilerce alinmasindan ve goruntuleme yontemlerinden faydalanilmamasindan kaynaklaniyor olabilir. Fine needle aspirationbiopsy experiences of head and neck masses in a two years period in Ondokuz Mayis University -50 cases The aim of this study was to compare the histopathological results of fine needle aspiration biopsy (FNAB)s in head and neck masses, and to evaluate the specifity and sensitivity for diagnosis. Data were obtained retrospectively from 50 patients who referred to our clinic with head and neck masses before surgery between August 2008 and July 2010. Twenty six patients (52%) were male and 24 (48%) were female. The mean and median ages of the patients were 54.3±17.8 and 55 respectively. Twenty nine patients (58%) had malignant histopathological etiology; in 10 patients (34.4%) FNAB was reported as “positive malignity”, 4 patients (13.7%) were reported as “negative malignity” and 15 patients (51.7%) were reported as “non-categorize” and/or “insuficient for assesment”. Twenty one patients (42%) had benign etiology; in 12 patients (57.1%) FNAB was reported as “negative malignity”, 9 patients (42.8%) were “non-categorize” and/or “insufficient for assessment”. There were no positive malignant reports obtained in the benign group. Squamous cell carcinoma is the most common diagnosis in malignant etiologies and nonspecific inflammation is the most common diagnosis in benign etiologies, which could be diagnosed with FNAB. FNAB method sensitivity was 71.4% , specifity was 100% and accuracy rate was found 84.6% . When compared with the literature, determination of the low level sensitivity and accuracy rates could be because biopsies were taken by different persons and the imaging techniques were not use. J. Exp. Clin. Med., 2012; 29:131-133
Databáze: OpenAIRE
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