Parathyroid hormone is significantly associated with body fat compartment in men but not in women following a hip fracture

Autor: Fulvia Vallero, Carlotta Castiglioni, Roberto Monaco, Rosa Tappero, Marco Di Monaco
Rok vydání: 2013
Předmět:
Zdroj: Aging Clinical and Experimental Research. 25:371-376
ISSN: 1720-8319
DOI: 10.1007/s40520-013-0057-2
Popis: Parathyroid hormone (PTH) exerts several actions beyond mineral metabolism and may affect body composition. The aim of our study was to assess the association between serum PTH and body fat compartment in hip fracture patients. We studied 575 of 630 inpatients with hip fracture consecutively admitted to our Rehabilitation ward. Dual-energy X-ray absorptiometry (DXA) was used to measure body composition. DXA scan was performed 18.5 ± 8.6 (mean ± SD) days after hip fracture occurrence. A blood sample was collected within 4 days after DXA scan. In each subject, we evaluated PTH, 25-hydroxyvitamin D, calcium, phosphate, albumin, magnesium, and creatinine. Glomerular filtration rate was estimated by a conventional formula. In the 57 men, we found a significant correlation between PTH and both body mass index (BMI) (ρ = 0.37; p = 0.020) and trunk fat percentage (ρ = 0.62; p
Databáze: OpenAIRE