Efficacy of phytosterols and fish-oil supplemented high-oleic-sunflower oil rich diets in hypercholesterolemic growing rats
| Autor: | Patricia Rodriguez, Fima Lifshitz, Patricia Mónica Boyer, Silvia María Friedman, Elisa Vanesa Macri, Clarisa Bozzini, Estefania Alsina |
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| Rok vydání: | 2016 |
| Předmět: |
Male
food.ingredient Hypercholesterolemia Blood lipids 030209 endocrinology & metabolism Weaning 030204 cardiovascular system & hematology Diet High-Fat 03 medical and health sciences chemistry.chemical_compound Random Allocation 0302 clinical medicine food Fish Oils Dietary Fats Unsaturated medicine Animals Plant Oils Sunflower Oil Food science Rats Wistar Olive Oil Triglycerides medicine.diagnostic_test Cholesterol Phytosterol Sunflower oil Anticholesteremic Agents Cholesterol HDL Phytosterols Fish oil Oleic acid chemistry Dietary Supplements Butter Diet Atherogenic lipids (amino acids peptides and proteins) Lipid profile Food Science Oleic Acid |
| Zdroj: | International journal of food sciences and nutrition. 67(4) |
| ISSN: | 1465-3478 |
| Popis: | Phytosterols (P) and fish-oil (F) efficacy on high-oleic-sunflower oil (HOSO) diets were assessed in hypercholesterolemic growing rats. Controls (C) received a standard diet for 8 weeks; experimental rats were fed an atherogenic diet (AT) for 3 weeks, thereafter were divided into four groups fed for 5 weeks a monounsaturated fatty acid diet (MUFA) containing either: extra virgin olive oil (OO), HOSO or HOSO supplemented with P or F. The diets did not alter body weight or growth. HOSO-P and HOSO-F rats showed reduced total cholesterol (T-chol), non-high-density lipoprotein-cholesterol (non-HDL-chol) and triglycerides and increased HDL-chol levels, comparably to the OO rats. Total body fat (%) was similar among all rats; but HOSO-F showed the lowest intestinal, epididymal and perirenal fat. However, bone mineral content and density, and bone yield stress and modulus of elasticity were unchanged. Growing hypercholesterolemic rats fed HOSO with P or F improved serum lipids and fat distribution, but did not influence material bone quality. |
| Databáze: | OpenAIRE |
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