Comparative Effectiveness of Pediatric Integrative Medicine: A Pragmatic Cluster-Controlled Trial
| Autor: | Hsing Jou, Michael Schlegelmilch, Sunita Vohra, Maria Spavor, Beverly Wilson, Andrew S. Mackie, Dawn Hartfield, Paul E. Grundy, Salima Punja, Jennifer Conway |
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| Rok vydání: | 2021 |
| Předmět: |
integrative medicine
complementary therapies medicine.medical_specialty pediatrics business.industry Nausea RJ1-570 Article law.invention Clinical trial Pharmacotherapy Randomized controlled trial law Rating scale Pediatrics Perinatology and Child Health medicine Vomiting Anxiety Integrative medicine medicine.symptom Intensive care medicine business |
| Zdroj: | Children Volume 8 Issue 4 Children, Vol 8, Iss 311, p 311 (2021) |
| ISSN: | 2227-9067 |
| DOI: | 10.3390/children8040311 |
| Popis: | Symptoms of pain, nausea/vomiting, and anxiety (PNVA) are highly prevalent in pediatric inpatients. Poorly managed symptoms can lead to decreased compliance with care, and prolonged recovery times. Pharmacotherapy used to manage PNVA symptoms is of variable effectiveness and carries safety risks. Complementary therapies to manage these symptoms are gaining popularity due to their perceived benefits and low risk of harm. Pediatric integrative medicine (PIM) is the combination of complementary therapies with conventional medicine in pediatric populations. A two-arm, cluster-controlled, pragmatic clinical trial was carried out to compare the effectiveness of a PIM service in conjunction with usual care, versus usual care only to treat PNVA symptoms in hospitalized pediatric patients. The primary outcome was the improvement of PNVA symptom severity using a 10-point numerical rating scale. Participant enrollment occurred between January 2013 and January 2016. A total of 872 participants (usual care n = 497 PIM n = 375) were enrolled. The PIM therapies significantly reduced PNVA symptom severity (p < 0.001). This study found that a hospital-based PIM service is both safe and effective for alleviating PNVA symptoms. Future research should carry out this work in other pediatric inpatient divisions, and in other sites to determine the reproducibility of findings. |
| Databáze: | OpenAIRE |
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