Autoimmune pancreatitis associated with retroperitoneal fibrosis mimicking cholangiocarcinoma
| Autor: | Domna Fanidou, Georgios Papadopoulos, Nikolaos Filippou, Panagiotis Skandalakis, Dimitrios Filippou, Anastasia Katseli |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Autoimmune disease
medicine.medical_specialty Abdominal pain business.industry Case Report Jaundice medicine.disease Retroperitoneal fibrosis Microbiology Gastroenterology 3. Good health 03 medical and health sciences Distal Common Bile Duct 0302 clinical medicine Infectious Diseases 030220 oncology & carcinogenesis Internal medicine Medicine Pancreatitis 030211 gastroenterology & hepatology Parasitology Differential diagnosis medicine.symptom business Autoimmune pancreatitis |
| Zdroj: | Oxford Medical Case Reports |
| ISSN: | 2053-8855 |
| DOI: | 10.1093/omcr/omy056 |
| Popis: | Autoimmune pancreatitis (AIP) is a rare systematic autoimmune disease that causes chronic pancreatitis. Type 1-AIP (IgG4-related disease) may involve other organs as well. In this report we are presenting a case of a 74-year-old man with obstructive abdominal pain jaundice, mild and a history of retroperitoneal fibrosis and hydronephrosis. Labs were remarkable for hyperbilirubinemia, high serum IgG4 levels, mildly elevated CA 19–9, elevated rheumatoid factor and new onset diabetes. MRI revealed pancreatic enlargement, dilated intrahepatic bile ducts and stricture of the distal common bile duct concerning for cholangiocarcinoma. EUS-FNA biopsy was negative for malignancy but showed findings of pancreatitis. The diagnosis of type 1-AIP was made and the patient was treated with steroids. After one month of treatment jaundice and MRI findings resolved. It is important to include AIP in the differential diagnosis of pancreatic conditions causing obstructive jaundice, especially in the presence of other autoimmune conditions like retroperitoneal fibrosis. |
| Databáze: | OpenAIRE |
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