Computer-Assisted Evaluation of Retinal Vessel Diameter in Retinitis Pigmentosa
| Autor: | Dario Pasquale Mucciolo, Gianni Virgili, Vittoria Murro, Bianca Terzuoli, Claudia Zoppetti, Stanislao Rizzo, Andrea Sodi, Alessandro Mecocci |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Fundus Oculi Visual Acuity Fundus (eye) Retina Young Adult 03 medical and health sciences Cellular and Molecular Neuroscience chemistry.chemical_compound 0302 clinical medicine Ophthalmology Retinitis pigmentosa Electroretinography Humans Medicine Diagnosis Computer-Assisted Fluorescein Angiography business.industry Disease progression Reproducibility of Results Retinal Vessels Retinal General Medicine medicine.disease Sensory Systems Retinal vessel Vessel diameter medicine.anatomical_structure chemistry 030221 ophthalmology & optometry Female business Retinitis Pigmentosa 030217 neurology & neurosurgery Retinal Dystrophies |
| Zdroj: | Ophthalmic Research. 56:139-144 |
| ISSN: | 1423-0259 0030-3747 |
| DOI: | 10.1159/000446843 |
| Popis: | Purpose: The evaluation of retinal vessel attenuation is very subjective and not sufficiently reliable in patients with retinitis pigmentosa (RP). We tested semiautomatic software capable of obtaining real-time measurements of vessel diameter. Methods: Retinal vessel diameter was calculated in 25 RP subjects and in 20 healthy controls. The Mann-Whitney test was used to compare the average values of RP patients with those of controls and subgroups of RP patients with different clinical features. Results: The retinal vessel diameter was significantly smaller in RP patients than in controls (p < 0.001). In particular, vessel diameters were smaller in older subjects, in patients with worse ERG responses, and in patients with more severe visual field loss. Conclusions: Computer-assisted analysis of retinal fundus pictures may be helpful in the diagnosis of RP and in monitoring disease progression. |
| Databáze: | OpenAIRE |
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