Hair straightening products and the risk of occupational formaldehyde exposure in hairstylists
| Autor: | Mohamed A. Ahmed Aglan, Ghada N. Mansour |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Genetic Markers Health Toxicology and Mutagenesis Buccal swab Group ii Formaldehyde Hair Preparations 010501 environmental sciences Toxicology medicine.disease_cause 01 natural sciences 03 medical and health sciences chemistry.chemical_compound Young Adult 0302 clinical medicine Occupational hygiene Occupational Exposure medicine Respiratory Hypersensitivity Humans Lymphocytes Hair straightening 0105 earth and related environmental sciences Pharmacology Chemical Health and Safety Micronucleus Tests business.industry Public Health Environmental and Occupational Health Mouth Mucosa General Medicine chemistry Egypt Female business Micronucleus 030217 neurology & neurosurgery FORMALDEHYDE EXPOSURE Genotoxicity DNA Damage |
| Zdroj: | Drug and chemical toxicology. 43(5) |
| ISSN: | 1525-6014 |
| Popis: | Hair straitening products are widely used by hairstylists. Many keratin-based hair smoothing products contain formaldehyde. This study aimed to investigate occupational formaldehyde exposure among hairstylists dealing with hair straightening products and the relation between genotoxicity biomarkers and the short-term formaldehyde exposure concentrations and the working years. The study was carried out in Cairo, Egypt on 60 hairstylists use hair straightening products divided into two groups according to the working years. All hairstylists were subjected to micronucleus (MN) frequencies in both epithelial buccal cells (EBC) and peripheral blood lymphocytes (PBL). Fifteen-minute (min) formaldehyde exposure concentrations were measured at workplace during hair straightening procedure. Fifteen-minute formaldehyde concentrations in both groups exceeded the National Institute for Occupational Safety and Health and the American Conference of Governmental Industrial Hygienist thresholds levels. The MN frequencies in EBC and PBL showed a significant increase in group II in comparison to control and group I, which in turn showed a significant increase in MN frequency in PBL and a nonsignificant increase in the MN frequency in EBC when compared to control. A positive correlation was found between genotoxicity biomarkers and working years. Occupational exposures to hair straightening products in the studied hairstylist were found to expose them to formaldehyde concentrations that exceeded the standard limits. All selected genotoxicity biomarkers showed a significant increase in exposed workers and were positively correlated to the duration of exposure. |
| Databáze: | OpenAIRE |
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