Isolation and Characterization of Wear Debris Generated in Patients Wearing Polyethylene Hylamer Inserts, Gamma Irradiated in Air
| Autor: | Susanna Stea, Concezio Fagnano, Matteo Reggiani, Aldo Toni, B. Antonietti, M. Visentin, Stefano Squarzoni |
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| Přispěvatelé: | M. Visentin, S. Stea, S. Squarzoni, M. Reggiani, C. Fagnano, B. Antonietti, A. Toni |
| Rok vydání: | 2005 |
| Předmět: |
Male
SCANNING ELECTRON MICROSCOPY Materials science 0206 medical engineering Wear debris Biomedical Engineering 02 engineering and technology Spectrum Analysis Raman Biomaterials 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Materials Testing Humans In patient Irradiation Composite material Aged 030222 orthopedics Air Sterilization Middle Aged Polyethylene 020601 biomedical engineering Prosthesis Failure WEAR chemistry HYLAMER Gamma Rays Microscopy Electron Scanning Female Hip Joint Hip Prosthesis Biomedical engineering |
| Zdroj: | Journal of biomaterials applications 20:2 (2005): 103–121. info:cnr-pdr/source/autori:M. VISENTIN, S. STEA, S. SQUARZONI, M. REGGIANI, C. FAGNANO, B. ANTONIETTI, A. TONI,/titolo:Isolation and characterization of wear debris generated in patients wearing polyethylene Hylamer inserts, gamma irradiated in air,/doi:/rivista:Journal of biomaterials applications/anno:2005/pagina_da:103/pagina_a:121/intervallo_pagine:103–121/volume:20:2 |
| ISSN: | 1530-8022 0885-3282 |
| DOI: | 10.1177/0885328205049407 |
| Popis: | Hylamer polyethylene was used in the early 1990s to make hip-joint components. Clinical experience has shown that these components, if sterilized by gamma rays in the presence of oxygen, are easily affected by wear, which then leads to osteolysis. The authors analyzed polyethylene wear particles in seven patients who had received Hylamer polyethylene implants sterilized by gamma rays in air and had suffered prosthetic loosening. The results were compared to those of six controls, who had received traditional polyethylene implants, sterilized by the same method. The frequency distribution of globular and fibrillar particles was similar in both groups (38.5% in Hylamer, 45.2% in controls). The globular particles in the Hylamer samples had a mean area of 0.12 mm2, which was significantly lesser than that of the controls (0.30 mm2). The width of fibrillar particles in the Hylamer samples was significantly lesser than that of the controls. Therefore, the two materials, despite undergoing the same type of sterilization, produced different types of wear, due to their different properties. In conclusion, the difference in the morphology of Hylamer polyethylene wear particles in comparison with PCA might have caused a more intensive biological response, early and massive osteolysis, and therefore, early loosening. |
| Databáze: | OpenAIRE |
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