Is ESR Important for Predicting Post-ERCP Pancreatitis?
| Autor: | Esmaeil Shamsi Afzali, Siavash zafar Doagoo, Amir Houshang Mohammad Alizadeh, Catherine Behzad, Mohammad Reza Zali, Mirhadi Mousavi, Dariush Mirsattari |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Endoscopic retrograde cholangiopancreatography Referral medicine.diagnostic_test business.industry pancreatitis Gastroenterology complication Odds ratio Disease medicine.disease cholangiopancreatography Recurrent pancreatitis Internal medicine medicine Hyperamylasemia Pancreatitis lcsh:Diseases of the digestive system. Gastroenterology lcsh:RC799-869 Complication business Original Research Biomedical engineering |
| Zdroj: | Clinical Medicine Insights: Gastroenterology, Vol 8 (2015) Clinical Medicine Insights. Gastroenterology Clinical Medicine Insights: Gastroenterology, Vol 2015, Iss 8, Pp 23-27 (2015) |
| ISSN: | 1179-5522 |
| Popis: | Background Pancreatitis remains the most common complication of endoscopic retrograde cholangiopancreatography (ERCP), resulting in substantial morbidity and occasional mortality. There are notable controversies and conflicting reports about risk factors of post-ERCP pancreatitis (PEP). Aim To evaluate the potential risk factors for PEP at a referral tertiary center, as a sample of the Iranian population. Materials and Methods Baseline characteristics and clinical as well as paraclinical information of 780 patients undergoing diagnostic and therapeutic ERCP at Taleghani hospital in Tehran between 2008 and 2012 were reviewed. Data were collected prior to the ERCP, at the time of the procedure, and 24-72 hours after discharge. PEP was diagnosed according to consensus criteria. Results Of the 780 patients who underwent diagnostic ERCP, pancreatitis developed in 26 patients (3.3%). In the multivariable risk model, significant risk factors with adjusted odds ratios (ORs) were age 30 (OR = 6.414, P < 0.001). Female gender, history of recurrent pancreatitis, pre-ERCP hyperamylasemia, and difficult or failed cannulation could not predict PEP. There was no significant difference in the rate of PEP in wire-guided cannulation versus biliary cannulation using a sphincterotome and contrast injection as the conventional method. Conclusions Performing ERCP may be safer in the elderly. Patients with high ESR may be at greater risk of PEP, which warrants close observation of these patients for signs of pancreatitis after ERCP. |
| Databáze: | OpenAIRE |
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