Hydroxyurea Initiation Among Children With Sickle Cell Anemia
| Autor: | Sarah L. Reeves, Jennifer P. Gondhi, Lynda D. Lisabeth, Hannah K. Jary, Jean L. Raphael, Kevin J. Dombkowski |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Adolescent Demographics Anemia Sickle Cell Logistic regression Article 03 medical and health sciences 0302 clinical medicine Antisickling Agents Health care medicine Humans Hydroxyurea Medical prescription Child Medicaid business.industry Infant Emergency department Patient Acceptance of Health Care medicine.disease United States Sickle cell anemia Administrative claims Hospitalization Child Preschool 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Female business 030215 immunology |
| Zdroj: | Clin Pediatr (Phila) |
| ISSN: | 1938-2707 0009-9228 |
| Popis: | This study assesses characteristics of children with sickle cell anemia associated with hydroxyurea initiation. Medicaid administrative claims from 6 states (2005-2012) were used to identify children with sickle cell anemia enrolled in Medicaid for ≥2 years. Hydroxyurea use was defined as >30 days’ supply of filled prescriptions. Children were classified as initiators (no use in year 1; use in year 2) or nonusers (no use in either year). Logistic regression was used to estimate associations between initiation, health care encounters, and demographics. A total of 4435 children were enrolled for 2 years during the study period; 885 (20.0%) initiators and 3080 (69.4%) nonusers. Children had an annual mean of 2.0 sickle cell disease–related inpatient admissions (SD = 2.2), 8.2 sickle cell disease–related outpatient visits (SD = 7.2), and 3.6 emergency department visits (SD = 3.5). The odds of initiating hydroxyurea increased with increasing health care utilization, age, and calendar year (all P values |
| Databáze: | OpenAIRE |
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