An overview of hazard and risk assessment of the OECD high production volume chemical category—Long chain alcohols [C6–C22] (LCOH)
| Autor: | Christoph Schäfers, Allen M. Nielsen, Hans Sanderson, Gauke Veenstra, Kathleen Stanton, Yutaka Kasai, Peter R. Fisk, Scott D. Dyer, Andreas Willing, Scott E. Belanger, Richard Sedlak |
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| Přispěvatelé: | Publica |
| Rok vydání: | 2009 |
| Předmět: |
High production volume chemicals
Health Toxicology and Mutagenesis Risk Assessment Aquatic toxicology Toxicology Environmental monitoring Animals Humans Production (economics) Mammals business.industry Public Health Environmental and Occupational Health General Medicine Chemical industry Environmental economics Pollution Hazard Biodegradation Environmental Daphnia Solubility Chemical Industry Environmental science Fatty Alcohols Volatilization Risk assessment business Long chain Water Pollutants Chemical Environmental Monitoring |
| Zdroj: | Sanderson, H, Belanger, S, Fisk, P, Schaefers, C, Veenstra, G, Nielsen, A, Kasai, Y, Willing, A, Dyer, S, Stanton, K & Sedlak, R 2009, ' An overview of hazard and risk assessment of the OECD high production volume chemical category-long chain alcohols [C6-C22] (LCOH) ', Ecotoxicology and Environmental Safety, vol. 72, no. 4, pp. 973-979 . https://doi.org/10.1016/j.ecoenv.2008.10.006 |
| ISSN: | 0147-6513 |
| DOI: | 10.1016/j.ecoenv.2008.10.006 |
| Popis: | This review summarizes the findings of the assessment report for the category, long chain alcohols (LCOH) with a carbon chain length range of C(6)-C(22) covering 30 substances, and >1.5million tonnes/year consumed globally. The category was evaluated under the Organization for Economic Co-operation and Development (OECD) high production volume chemicals program in 2006. The main findings of the assessment include: (1) no unacceptable human or environmental risks were identified; (2) these materials are rapidly and readily biodegradable; (3) a parabolic relationship was demonstrated between carbon chain length and acute and chronic aquatic toxicity; (4) category-specific (quantitative) structure-activity relationships were developed enabling prediction of properties across the entire category; (5) LCOH occur naturally in the environment in an equilibrium between synthesis and degradation; (6) industry coming together and sharing resources results in minimizing the need for additional animal tests, produces cost savings, and increases scientific quality of the assessment. |
| Databáze: | OpenAIRE |
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