Acute Staphylococcal Enterocolitis Complicating Oral Neomycin Therapy in Cirrhosis

Autor: W. A. Tisdale, Gerald Klatskin, L. F. Fenster
Rok vydání: 1960
Předmět:
Zdroj: New England Journal of Medicine. 263:1014-1016
ISSN: 1533-4406
0028-4793
DOI: 10.1056/nejm196011172632009
Popis: THE oral administration of certain poorly absorbed antibiotics is widely accepted as an important measure in the management of the neuropsychiatric complications of severe liver disease. Of these anti-bacterial agents, neomycin has proved the most satisfactory, effectively suppressing intestinal flora with a minimum of undesirable or harmful side effects.1 2 3 Although diarrhea,1 steatorrhea,4 occasional systemic absorption of the drug5 , 6 and mild monilial superinfection2 have occurred in a few cases, to our knowledge no serious complications due to neomycin-resistant organisms have been reported to follow the use of this drug in the treatment of impending or overt hepatic coma. Recently, however, we . . .
Databáze: OpenAIRE