Deafness in an auditory specialist, the big brown bat (Eptesicus fuscus)
| Autor: | Madison M. Weinberg, Susanne Sterbing, Amanda M. Lauer, Laurel A. Screven, Nazrawit A. Retta, Cynthia F. Moss, Jamie L. Peterson, Katrina M. Schrode |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
biology Hearing loss Stimulation Sensory system Human echolocation Deafness Audiology biology.organism_classification Sensory Systems medicine.anatomical_structure Acoustic Stimulation Hearing Eptesicus fuscus Chiroptera Echolocation otorhinolaryngologic diseases Auditory nuclei medicine Animals sense organs Brainstem medicine.symptom Spiral ganglion |
| Zdroj: | Hearing Research. 412:108377 |
| ISSN: | 0378-5955 |
| Popis: | Bats are long-lived animals that show presumed resistance to noise-induced and age-related hearing loss, which has been attributed to their dependence on sound processing for survival. Echolocation and basic auditory functions have been studied extensively in the big brown bat (Eptesicus fuscus), an insectivorous microchiropteran species. We conducted hearing tests and analysis of cochlear sensory cells in a group of big brown bats that exhibited anomalies in behavioral sonar tracking experiments and/or lacked neural responses to acoustic stimulation in subcortical auditory nuclei. We show for the first time the presence of profound deafness and extensive cochlear damage in an echolocating bat species. Auditory brainstem responses were abnormal or absent in these bats, and histological analyses of their cochleae revealed extensive loss of hair cells, supporting cells, and spiral ganglion neurons. The underlying cause of deafness is unknown. |
| Databáze: | OpenAIRE |
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