A Critical Review on 3D-printed Dosage Forms
| Autor: | Ilias El Aita, Julian Quodbach, Hanna Ponsar |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Dosage Forms
Pharmacology Engineering 3d printed business.industry Manufacturing process 02 engineering and technology 021001 nanoscience & nanotechnology 030226 pharmacology & pharmacy Manufacturing engineering Dosage form Drug Liberation 03 medical and health sciences 0302 clinical medicine Literature research Printing Three-Dimensional Drug Discovery Drug release Humans 0210 nano-technology business |
| Zdroj: | Current Pharmaceutical Design. 24:4957-4978 |
| ISSN: | 1381-6128 |
| DOI: | 10.2174/1381612825666181206124206 |
| Popis: | Background: In the last decades, 3D-printing has been investigated and used intensively in the field of tissue engineering, automotive and aerospace. With the first FDA approved printed medicinal product in 2015, the research on 3D-printing for pharmaceutical application has attracted the attention of pharmaceutical scientists. Due to its potential of fabricating complex structures and geometrics, it is a highly promising technology for manufacturing individualized dosage forms. In addition, it enables the fabrication of dosage forms with tailored drug release profiles. Objective: The aim of this review article is to give a comprehensive overview of the used 3D-printing techniques for pharmaceutical applications, including information about the required material, advantages and disadvantages of the respective technique. Methods: For the literature research, relevant keywords were identified and the literature was then thoroughly researched. Conclusion: The current status of 3D-printing as a manufacturing process for pharmaceutical dosage forms was highlighted in this review article. Moreover, this article presents a critical evaluation of 3D-printing to control the dose and drug release of printed dosage forms. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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