Residue-specific incorporation of non�canonical amino acids into proteins: recent developments and applications

Autor:	Ying Y. Lu, James A. Van Deventer, Jeremiah A. Johnson, David A. Tirrell
Jazyk:	angličtina
Rok vydání:	2010
Předmět:	chemistry.chemical_classification Proteins Biology Biochemistry Article Analytical Chemistry Amino acid Amino Acyl-tRNA Synthetases Residue (chemistry) chemistry Non canonical Animals Humans Amino Acids
Popis:	Residue-specific incorporation of non-canonical amino acids into proteins allows facile alteration and enhancement of protein properties. In this review, we describe recent technical developments and applications of residue-specific incorporation to problems ranging from elucidation of biochemical mechanisms to engineering of protein-based biomaterials. We hope to inform the reader of the ease and broad utility of residue-specific non-canonical amino acid incorporation with the goal of inspiring investigators outside the field to consider applying this tool to their own research.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98aed11520b667daa90c014030dfc21 https://europepmc.org/articles/PMC3008400/ Zobrazit plný text záznamu