Synthesis of a Glycolipidic Amphiphilic Nitrone as a New Spin Trap

Autor:	Paul Tordo, Ange Polidori, Florence Chalier, Olivier Ouari, Bernard Pucci
Rok vydání:	1999
Předmět:	Tris chemistry.chemical_classification chemistry.chemical_compound Membrane chemistry Pulmonary surfactant Radical Organic Chemistry Amphiphile Moiety Hydroxymethyl Photochemistry Nitrone
Zdroj:	The Journal of Organic Chemistry. 64:3554-3556
ISSN:	1520-6904 0022-3263
DOI:	10.1021/jo982343+
Popis:	The synthesis of a new amphiphilic nitrone, A, derived from a digalactosyl tris(hydroxymethyl)aminomethane bearing a perfluorocarbon chain is described. A exhibited a surfactant behavior (cmc = 1.6 x 10(-)(5) mol/L), and the specific recognition of the galactosyl moiety grafted on A by the KbCWL1 membrane lectin was established. Preliminary experiments showed that A was able to trap free radicals in aqueous media, the shape of the observed ESR spectra being strongly dependent upon the nature of the trapped free radical.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97ee527fc47e87543a0f2b369fa5f7e https://doi.org/10.1021/jo982343+ Zobrazit plný text záznamu