Blood Pressure and Brain Lesions in Patients With Atrial Fibrillation

Autor: Aeschbacher, Stefanie, Blum, Steffen, Meyre, Pascal B., Coslovsky, Michael, Vischer, Annina S., Sinnecker, Tim, Rodondi, Nicolas, Beer, Jürg H., Moschovitis, Giorgio, Moutzouri, Elisavet, Hunkeler, Christof, Burkard, Thilo, Eken, Ceylan, Roten, Laurent, Zuern, Christine S., Sticherling, Christian, Wuerfel, Jens, Bonati, Leo H., Conen, David, Osswald, Stefan, Kühne, Michael, Swiss-AF Investigators
Přispěvatelé: Auberson, Chloé, Ceylan, Selinda, Doerpfeld, Simone, Girod, Marc, Hennings, Elisa, Krisai, Philipp, Monsch, Andreas U., Müller, Christian, Springer, Anne, Voellmin, Gian, Aujesky, Drahomir, Fischer, Urs, Fuhrer, Juerg, Jung, Simon, Mattle, Heinrich, Adam, Luise, Elodie Aubert, Carole, Feller, Martin, Loewe, Axel, Schneider, Claudio, Flückiger, Tanja, Groen, Cindy, Ehrsam, Lukas, Hellrigl, Sven, Nuoffer, Alexandra, Rakovic, Damiana, Schwab, Nathalie, Wenger, Rylana, Müller, Andreas, Beynon, Christopher, Dillier, Roger, Deubelbeiss, Michèle, Eberli, Franz, Franzini, Christine, Juchli, Isabel, Liedtke, Claudia, Nadler, Jacqueline, Obst, Thayze, Roth, Jasmin, Schlomowitsch, Fiona, Schneider, Xiaoye, Studerus, Katrin, Tynan, Noreen, Weishaupt, Dominik, Fontana, Simone, Kuest, Silke, Scheuch, Karin, Hischier, Denise, Bonetti, Nicole, Grau, Alexandra, Villinger, Jonas, Laube, Eva, Baumgartner, Philipp, Filipovic, Mark, Frick, Marcel, Montrasio, Giulia, Leuenberger, Stefanie, Rutz, Franziska, Moccetti, Tiziano, Auricchio, Angelo, Anesini, Adriana, Camporini, Cristina, Conte, Giulio, Luce Caputo, Maria, Regoli, Francois, Ammann, Peter, Brenner, Roman, Altmann, David, Gemperle, Michaela, Hayoz, Daniel, Firmann, Mathieu, Foucras, Sandrine, Rime, Martine, Kobza, Richard, Berte, Benjamin, Justi, Virgina, Kellner-Weldon, Frauke, Mehmann, Brigitta, Meier, Sonja, Roth, Myriam, Ruckli-Kaeppeli, Andrea, Russi, Ian, Schmidt, Kai, Young, Mabelle, Zbinden, Melanie, Frangi-Kultalahti, Jane, Pin, Anica, Shah, Dipen, Ehret, Georg Benedikt, Gallet, Hervé, Guillermet, Elise, Lazeyras, François, Lövblad, Karl-Olof, Perret, Patrick, Tavel, Philippe, Teres Castillo, Cheryl, Schläpfer, Jürg, Lauriers, Nathalie, Méan, Marie, Salzmann, Sandrine, Stephan, Frank-Peter, Grêt, Andrea, Novak, Jan, Vitelli, Sandra, Di Valentino, Marcello, Gallino, Augusto, Witassek, Fabienne, Schwenkglenks, Matthias, Altermatt, Anna, Amann, Michael, Huber, Petra, Ruberte, Esther, Zuber, Vanessa, Benkert, Pascal, Dutilh, Gilles, Markovic, Milica, Neuschwander, Pia, Simon, Patrick, Schmid, Ramun
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Hypertension, Vol. 77, No 2 (2020) pp. 662-671
Hypertension (Dallas, Tex. : 1979)
ISSN: 0194-911X
Popis: Supplemental Digital Content is available in the text.
The association of blood pressure (BP) and hypertension with the presence of different types of brain lesions in patients with atrial fibrillation is unclear. BP values were obtained in a multicenter cohort of patients with atrial fibrillation. Systolic and diastolic BP was categorized in predefined groups. All patients underwent brain magnetic resonance imaging and neurocognitive testing. Brain lesions were classified as large noncortical or cortical infarcts, small noncortical infarcts, microbleeds, or white matter lesions. White matter lesions were graded according to the Fazekas scale. Overall, 1738 patients with atrial fibrillation were enrolled in this cross-sectional analysis (mean age, 73 years, 73% males). Mean BP was 135/79 mm Hg, and 67% of participants were taking BP-lowering treatment. White matter lesions Fazekas ≥2 were found in 54%, large noncortical or cortical infarcts in 22%, small noncortical infarcts in 21%, and microbleeds in 22% of patients, respectively. Compared with patients with systolic BP
Databáze: OpenAIRE
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