What is transfer factor?
| Autor: | L.G. Foster, S.R. Waldman, M. Lopez, A.A. Gottlieb |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Antigens
Fungal Sodium Transfer factor Size-exclusion chromatography Polynucleotides chemistry.chemical_element Blood Donors General Medicine Polypeptide chain Histoplasmin Sulfur Radioisotopes CANDIDA ANTIGEN Biochemistry chemistry Active component Chromatography Gel Leukocytes Methods Moiety Humans Hypersensitivity Delayed Dialysis Immunity Maternally-Acquired Candida |
| Zdroj: | Lancet (London, England). 2(7833) |
| ISSN: | 0140-6736 |
| Popis: | Leucocytes obtained from a donor sensitive to Candida antigen contain a factor (transfer factor) which transfers this sensitivity to non-sensitive recipients. This material is present in the dialysate of leucocyte lysates and can be purified therefrom by gel filtration. This immunologically active component of transfer factor seems to be more potent than the crude dialysate, and contains a moiety which is readily labelled by culturing the leucocytes in the presence of 35 S-labelled sodium sulphate. This labelled moiety has the properties of a short polypeptide chain joined to three or four R.N.A. bases. |
| Databáze: | OpenAIRE |
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