A Successful Mother and Neonate Outcome for a Woman with Essential Thrombocytosis and FV Leiden Heterozygosity
| Autor: | Irontianta Gkorezi-Ntavela, Serena Valsami, Marianna Politou, Panagiotis F. Christopoulos, Efrosyni Merkouri, Vasilios Telonis |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Pregnancy
medicine.medical_specialty Aspirin Thrombocytosis Obstetrics business.industry Obstetrics and Gynecology Case Report 030204 cardiovascular system & hematology medicine.disease Successful pregnancy Thrombosis lcsh:Gynecology and obstetrics Surgery Loss of heterozygosity 03 medical and health sciences Thromboelastometry 0302 clinical medicine Coagulation 030220 oncology & carcinogenesis medicine business lcsh:RG1-991 medicine.drug |
| Zdroj: | Case Reports in Obstetrics and Gynecology, Vol 2016 (2016) Case Reports in Obstetrics and Gynecology |
| ISSN: | 2090-6692 2090-6684 |
| Popis: | Essential thrombocytosis (ET) and FV Leiden heterozygosity represent an acquired and hereditable hypercoagulable state, respectively. An uncommon case of coexistence of ET and FV Leiden heterozygosity in a 36-year-old pregnant woman and her successful pregnancy outcome is described. She was considered to be at high risk of thrombosis during her pregnancy and she was treated with both prophylactic dose of LMWH and aspirin daily throughout her pregnancy and for a 6-week period postpartum. The efficacy of the anticoagulation treatment was monitored in various time points not only by measuring anti-Xa levels and D-Dimers but also with new coagulation methods such as rotation thromboelastometry and multiplate. Global assessment of coagulation using additional newer laboratory tests might prove useful in monitoring coagulation pregnancies at high risk for thrombosis. |
| Databáze: | OpenAIRE |
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