Effects of C17-Hydroxy-Steroids on Urinary 17-Ketosteroids in the Rat
| Autor: | A. C. Corcoran, Francesco Del Greco, Georges M. C. Masson |
|---|---|
| Rok vydání: | 1952 |
| Předmět: |
medicine.medical_specialty
Chemistry medicine.medical_treatment Urinary system General Biochemistry Genetics and Molecular Biology 17-Ketosteroids Body Fluids Rats Steroid Hydroxylation chemistry.chemical_compound Endocrinology Biochemistry Internal medicine medicine Animals Steroids Secretion Urinary Tract Hydroxysteroids Normal female Hormone |
| Zdroj: | Experimental Biology and Medicine. 80:354-357 |
| ISSN: | 1535-3699 1535-3702 |
| Popis: | SummaryA method is described for detecting precursors of urinary 17-KS in normal female rats. Using it, 2 pairs of compounds which differed in hydroxylation at C-17 were tested and those 2 possessing this grouping were found to be eliminated in part as urinary 17-KS. One 17-hydroxylated steroid, pregnenetriolone did not act as a 17-KS precursor. These observations bring into question the assumed secretion of adrenal androgens, since they are consistent with the view that such might arise from the degradation of non-an-drogenic hormones. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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