Serum β-Endorphin Levels in Morbidly Obese Patients: The Effect of Vertical Banded Gastroplasty

Autor: Anastasios J. Karayiannakis, D. Alexiou, G. G. Makri, Konstantinos N. Syrigos, Andrew P. Zbar, L. Athanasiadis, Elias Bastounis
Rok vydání: 1998
Předmět:
Zdroj: European Surgical Research. 30:409-413
ISSN: 1421-9921
0014-312X
DOI: 10.1159/000008606
Popis: The associations between serum β-endorphin levels and clinical and metabolic variables as well as β-endorphin changes after surgically induced weight loss were investigated in 43 morbidly obese patients. A significant positive correlation between β-endorphin and body weight, degree of body weight increase and ACTH was found preoperatively. Only body weight was independently associated with β-endorphin levels. Twelve months following vertical banded gastroplasty, there was an extensive weight loss in all patients and improvement in their metabolic profile. A significant reduction in β-endorphin levels which was proportional to the extent of weight loss was also observed.
Databáze: OpenAIRE