Successful treatment of cardiac haemangiomas with oral propranolol: a case series of two patients
| Autor: | Aphrodite Tzifa, Ioannis Polymerou, Pipina Bonou, Laura Martelius, Tiina Ojala |
|---|---|
| Přispěvatelé: | HUS Children and Adolescents, Clinicum, Children's Hospital, University of Helsinki, HUS Medical Imaging Center, Department of Diagnostics and Therapeutics |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Haemangioma
medicine.medical_specialty Population education Propranolol Infantile Intracardiac injection Hemangioma 030207 dermatology & venereal diseases 03 medical and health sciences Heart neoplasms 0302 clinical medicine 030225 pediatrics Neonatal Complete regression medicine Case Series Cardiac tumour education.field_of_study business.industry medicine.disease 3126 Surgery anesthesiology intensive care radiology 3. Good health body regions Radiology Presentation (obstetrics) Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | European Heart Journal: Case Reports |
| ISSN: | 2514-2119 |
| Popis: | BackgroundCardiac haemangiomas are extremely rare tumours with equivocal surgical outcomes. Haemangiomas appearing on other sites of the body have been successfully treated with oral propranolol. To the best of our knowledge, such treatment has not been tried to date for cardiac location of haemangiomas.Case summaryWe report two cases of neonatal cardiac haemangiomas, and we describe their presentation and characteristics, as well as how these were successfully treated with oral propranolol, with complete regression of the tumours within the 1st year of life.DiscussionDespite the rarity of cardiac haemangiomas, their presentation and complications could be dramatic with side-effects spanning from intracardiac space occupying phenomena to Kasabach–Merritt syndrome. Propranolol therapy, having been established for long now in the treatment of skin haemangiomas, should also be considered in cases of cardiac haemangiomas, particularly in the neonatal and infantile population. |
| Databáze: | OpenAIRE |
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