Neurophysiologic study in idiopathic overactive bladder
| Autor: | Naglaa Gadallah, Ihab Serag, Rowaida Hamdy Ali, Abeer K. El Zohiery, Mohamed Elwy |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
medicine.medical_specialty External anal sphincter Urology Pudendal nerve 030232 urology & nephrology Young Adult 03 medical and health sciences Pudendal Neuropathy 0302 clinical medicine Surveys and Questionnaires medicine Humans Pudendal Neuralgia 030219 obstetrics & reproductive medicine Reflex Abnormal Electromyography Urinary Bladder Overactive business.industry Urethral sphincter Anal wink Middle Aged medicine.disease Pudendal Nerve Urodynamics Cross-Sectional Studies Overactive bladder Somatosensory evoked potential Reflex Female Neurology (clinical) business |
| Zdroj: | Neurourology and Urodynamics. 38:223-230 |
| ISSN: | 0733-2467 |
| DOI: | 10.1002/nau.23834 |
| Popis: | Aim Idiopathic overactive bladder (OAB) is a prevalent, mystifying disorder with a questionable neurogenic background. We aimed to investigate the possible subtle neuropathic affection underlying its pathogenesis. Methods A cross-sectional cut off study was carried out on a series of 38 females with idiopathic OAB and 22 healthy matched female volunteers. The following was performed: symptom score questionnaire, determination of pudendal nerve terminal motor latency (PNTML), sacral reflexes' latencies, pudendal somatosensory evoked potentials, and needle electromyography of the external anal and urethral sphincters. Results A highly significant prolongation of PNTMLs and sacral reflexes latencies among the patients group was detected (P ≥ 0.001). Pudendal somatosensory evoked potentials showed non- significance among the two studied groups (P ≥ 0.05). External anal sphincter neuropathic affection was detected in 27 patients (71%) and external urethral sphincter neuropathic affection was detected in 30 patients (78.9%). The clitoral anal reflex showed the highest sensitivity and specificity among the neurophysiologic tests used in assessing the neuropathic affection (86.7 and 83%, respectively), followed by PNTML (83.3 and 80%, respectively). Conclusion Pudendal neuropathy is the dominating possible attributing factor in the pathogenesis underlying idiopathic OAB. An integrated clinical, urodynamic, and electro-physiological assessment is recommended for evaluation of any overactive bladder patients. |
| Databáze: | OpenAIRE |
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