Blood product needs and transfusion timelines for the multisite massive Paris 2015 terrorist attack: A retrospective analysis
| Autor: | Sophie Hamada, Frédéric Lapostolle, Anne François, Dominique Pateron, Bruno Riou, Arié Attias, Mathieu Raux, Thomas Pouget, Matthieu Langlois, Emmanuelle Dolla, Thibault Martinez, Pierre Carli, Jean-Pierre Tourtier, Bertrand Ludes, Anne-Laure Feral-Pierssens, Tobias Gauss, Etienne Gayat, Yves Castier, Youri Yordanov, Carl Ogereau, Alexandre Woloch, Sylvain Ausset |
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| Přispěvatelé: | Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Institute of cardiometabolism and nutrition (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Service des Urgences [CHU Saint-Antoine], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Saint-Antoine [AP-HP], Neurophysiologie Respiratoire Expérimentale et Clinique, Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Service d'urgence de médecine et de chirurgie [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP] |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Paris [SDV]Life Sciences [q-bio] Hemorrhage Critical Care and Intensive Care Medicine 03 medical and health sciences Plasma 0302 clinical medicine Injury Severity Score Blood product Epidemiology medicine Humans Mass Casualty Incidents Platelet Blood Transfusion Cause of death Retrospective Studies business.industry 030208 emergency & critical care medicine Retrospective cohort study 3. Good health Mass-casualty incident Red blood cell medicine.anatomical_structure Emergency medicine Surgery Female Terrorism business Erythrocyte Transfusion |
| Zdroj: | The Journal of Trauma and Acute Surgery The Journal of Trauma and Acute Surgery, Lippincott, Williams & Wilkins, 2020, 89 (3), pp.496-504. ⟨10.1097/TA.0000000000002729⟩ |
| ISSN: | 2163-0755 2163-0763 |
| Popis: | Objective Hemorrhage is the leading cause of death after terrorist attack, and the immediacy of labile blood product (LBP) administration has a decisive impact on patients' outcome. The main objective of this study was to evaluate the transfusion patterns of the Paris terrorist attack victims, November 13, 2015. Methods We performed a retrospective analysis including all casualties admitted to hospital, aiming to describe the transfusion patterns from admission to the first week after the attack. Results Sixty-eight of 337 admitted patients were transfused. More than three quarters of blood products were consumed in the initial phase (until November 14, 11:59 PM), where 282 packed red blood cell (pRBC) units were transfused along with 201 plasma and 25 platelet units, to 55 patients (16% of casualties). Almost 40% of these LBPs (134 pRBC, 73 plasma, 8 platelet units) were transfused within the first 6 hours after the attack. These early transfusions were massive transfusion (MT) for 20 (6%) of 337 patients, and the average plasma/red blood cell ratio was 0.8 for MT patients who received 366 (72%) of 508 LBPs.The median time from admission to pRBC transfusion was 57 (25-108) minutes and 208 (52-430) minutes for MT and non-MT patients, respectively. These same time intervals were 119 (66-202) minutes and 222 (87-381) minutes for plasma and 225 (131-289) minutes and 198 (167-230) minutes for platelets. Conclusion Our data suggest that improving transfusion procedures in mass casualty setting should rely more on shortening the time to bring LBP to the bedside than in increasing the stockpile. Level of evidence Epidemiological study, Therapeutic IV. |
| Databáze: | OpenAIRE |
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