Molecular Biology and Pharmacology of Galanin Receptors
| Autor: | Mary W. Walker, Kelli E. Smith, Theresa Branchek |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Receptors
Neuropeptide endocrine system Molecular Sequence Data Clone (cell biology) Galanin Galanin receptor Pharmacology Biology General Biochemistry Genetics and Molecular Biology History and Philosophy of Science In vivo Animals Humans Amino Acid Sequence Cloning Molecular Receptor Peptide sequence General Neuroscience digestive oral and skin physiology Molecular biology In vitro Rats nervous system Signal transduction Receptors Galanin Sequence Analysis hormones hormone substitutes and hormone antagonists Signal Transduction |
| Zdroj: | Annals of the New York Academy of Sciences. 863:94-107 |
| ISSN: | 1749-6632 0077-8923 |
| DOI: | 10.1111/j.1749-6632.1998.tb10687.x |
| Popis: | Galanin was first isolated 15 years ago. Diversity of galanin receptors has been suspected from the study of native tissues and functional responses to galanin and galanin-like peptides in vitro and in vivo. The recent application of molecular biologic techniques to clone galanin receptors has extended this diversity. So far, three galanin receptor subtypes, GALR1, GALR2, and GALR3, have been cloned from both human and rat. Their molecular structure, pharmacologic profiles, tissue distribution, and signal transduction properties have been partially elucidated. |
| Databáze: | OpenAIRE |
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