Association of Obstructive Sleep Apnea With Nighttime Blood Pressure in African Americans: The Jackson Heart Study
| Autor: | Na Guo, Tanya M. Spruill, Yuichiro Yano, John N. Booth, Marwah Abdalla, Stephen J Thomas, David A. Calhoun, Paul Muntner, Susan Redline, Dayna A. Johnson, Chandra L. Jackson, Mario Sims |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Ambulatory blood pressure Systole Population Blood Pressure Polysomnography Hypoxemia Diastole Internal medicine Internal Medicine medicine Humans Sleep study Hypoxia education Aged Sleep Apnea Obstructive education.field_of_study medicine.diagnostic_test business.industry Sleep apnea Original Contribution Blood Pressure Monitoring Ambulatory Middle Aged medicine.disease Circadian Rhythm Black or African American Obstructive sleep apnea Blood pressure Hypertension Cardiology Female medicine.symptom business |
| Zdroj: | Am J Hypertens |
| ISSN: | 1941-7225 0895-7061 |
| Popis: | BACKGROUND Obstructive sleep apnea (OSA), nocturnal hypertension, and nondipping systolic blood pressure (BP) are each highly prevalent among African Americans. However, few data are available on the association between OSA and nighttime BP in this population. METHODS We examined the association of OSA with nighttime BP among African Americans who completed 24-hour ambulatory BP monitoring (ABPM) at Exam 1 (2000–2004) of the Jackson Heart Study (JHS) and subsequently participated in the JHS Sleep Study (2012–2016). Type 3 home sleep apnea testing was used to assess OSA measures, including respiratory event index (REI4%) and percent sleep time RESULTS Among 206 participants who completed ABPM and participated in the Jackson Heart Sleep Study, 50.5% had nocturnal hypertension and 26.2% had moderate to severe OSA (REI4% ≥15 events/hour). After multivariable adjustment, each SD (13.3 events/hour) increase in REI4% was associated with 1.75 mm Hg higher nighttime DBP (95% confidence interval (CI): 0.38, 3.11) and a prevalence ratio of 1.11 (95% CI: 1.00, 1.24) for nocturnal hypertension. Each SD (10.4%) increase in nocturnal hypoxemia was associated with a 1.91 mm Hg higher nighttime SBP (95% CI: 0.15, 3.66). CONCLUSIONS Severity of OSA and nocturnal hypoxemia were associated with high nighttime BP in African American participants in the JHS. |
| Databáze: | OpenAIRE |
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