Synthesis of 'Dahlia-Like' Hydrophilic Fluorescent Carbon Nanohorn as a Bio-Imaging PROBE

Autor: Rajeshkumar Anbazhagan, Juin-Yih Lai, Vijaya Rohini Parasuraman, Hsieh-Chih Tsai, Perumalswamy Sekar Parasuraman
Rok vydání: 2019
Předmět:
Carbonation
chemistry.chemical_element
02 engineering and technology
010402 general chemistry
01 natural sciences
Micelle
Catalysis
Hydrothermal circulation
lcsh:Chemistry
Inorganic Chemistry
chemistry.chemical_compound
carbon nanohorn
Nafion
Spectroscopy
Fourier Transform Infrared
Physical and Theoretical Chemistry
Porosity
lcsh:QH301-705.5
Molecular Biology
Spectroscopy
Fluorescent Dyes
Communication
Organic Chemistry
Dahlia
General Medicine
021001 nanoscience & nanotechnology
Fluorescence
Carbon
Molecular Imaging
Nanostructures
0104 chemical sciences
Computer Science Applications
bio-imaging
lcsh:Biology (General)
lcsh:QD1-999
chemistry
Chemical engineering
hydrothermal method
Molecular Probes
cardiovascular system
0210 nano-technology
Hydrophobic and Hydrophilic Interactions
circulatory and respiratory physiology
Zdroj: International Journal of Molecular Sciences, Vol 20, Iss 12, p 2977 (2019)
International Journal of Molecular Sciences
ISSN: 1422-0067
DOI: 10.3390/ijms20122977
Popis: Carbon nanohorns (CNH) were synthesized by a simple conventional hydrothermal method in this study. The CNHs were prepared by the chemical oxidation from the carbonation of Nafion (catalyst) with heparin (carbon resource). The formation of CNH involved two major steps, as described followed. First, the formation of carbon nanorice (CNR) was achieved by carbonation and self-assembly of heparin inside the Nafion structure. Second, the further oxidation of CNR resulted the heterogeneous and porous micelle domains showed at the outer layer of the CNR particles. These porous domains exhibited hydrophobic carbon and resulted self-assembly of the CNR to form the structure of CNHs. The resulting CNHs aggregated into a “dahlia-like” morphology with fluorescence in a diameter of 50−200 nm. The “dahlia-like” CNH showed better fluorescence (450nm) than CNR particles because of the presence of more structural defect. These findings suggest that the hydrophilic fluorescent carbon nanohorns (HFCNHs) synthesized in this study have the potential to be used for in vitro bio-imaging
Databáze: OpenAIRE
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