Privileged Phosphine-Based Metal–Organic Frameworks for Broad-Scope Asymmetric Catalysis

Autor:	Teng Zhang, Takahiro Sawano, Galen Tsun, Jenny V. Lockard, Yuan Chen, Joseph M. Falkowski, Wenbin Lin
Rok vydání:	2014
Předmět:	chemistry.chemical_classification Alkene Aryl Enantioselective synthesis General Chemistry Biochemistry Combinatorial chemistry Catalysis chemistry.chemical_compound Colloid and Surface Chemistry chemistry Organic chemistry Metal-organic framework Linker Alkyl Phosphine
Zdroj:	Journal of the American Chemical Society. 136:5213-5216
ISSN:	1520-5126 0002-7863
DOI:	10.1021/ja500090y
Popis:	A robust and porous Zr metal–organic framework (MOF) based on a BINAP-derived dicarboxylate linker, BINAP-MOF, was synthesized and post-synthetically metalated with Ru and Rh complexes to afford highly enantioselective catalysts for important organic transformations. The Rh-functionalized MOF is not only highly enantioselective (up to >99% ee) but also 3 times as active as the homogeneous control. XAFS studies revealed that the Ru-functionalized MOF contains Ru-BINAP precatalysts with the same coordination environment as the homogeneous Ru complex. The post-synthetically metalated BINAP-MOFs provide a versatile family of single-site solid catalysts for catalyzing a broad scope of asymmetric organic transformations, including addition of aryl and alkyl groups to α,β-unsaturated ketones and hydrogenation of substituted alkene and carbonyl compounds.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f949439bc8ecc66cd6b7ac126a8fec23 https://doi.org/10.1021/ja500090y Zobrazit plný text záznamu