The effect of macroglobulins on flocculation tests
| Autor: | Viallet A, R. Fauvert, L. Hartmann |
|---|---|
| Rok vydání: | 1963 |
| Předmět: |
Electrophoresis
Flocculation animal structures Chemical Phenomena Globulin Clinical Biochemistry Beta-Globulins Beta globulins Biochemistry fluids and secretions Liver Function Tests immune system diseases Macroglobulins medicine Humans skin and connective tissue diseases Immunoelectrophoresis Flocculation test Chromatography biology Chemistry Biochemistry (medical) Waldenstrom macroglobulinemia Macroglobulinemia Gamma globulin Blood Proteins Flocculation Tests General Medicine medicine.disease biology.protein Serum Globulins gamma-Globulins Waldenstrom Macroglobulinemia circulatory and respiratory physiology |
| Zdroj: | Clinica Chimica Acta. 8:872-883 |
| ISSN: | 0009-8981 |
| DOI: | 10.1016/0009-8981(63)90010-x |
| Popis: | Experiments, in vitro, on the progressive enrichment of normal sera by macroglobulins show that the latter is a factor of positive flocculation reactions. Similar experiments with normal pure y-globulins show negative results. However, the addition of a relatively small and constant amount of macroglobulins to increasing quantities of y-globulins in normal sera induces flocculation; this suggests that the macroglobulins have a “starter effect”. The use in these experiments of macroglobulins from sera of subjects suffering from Waldenstrom macroglobulinemia disease has been discussed. Literature concerning the mechanism of flocculation reactions has been reviewed. |
| Databáze: | OpenAIRE |
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