Are magnetic resonance imaging undetectable prostate tumours clinically significant? Results of histopathological analyses
| Autor: | Seyed Behzad Jazayeri, Young Suk Kwon, Shemille A. Collingwood, Karl Coutinho, Kristian D. Stensland, Maria Katsigeorgis, Lindsay Haines, David B. Samadi, Adele R. Hobbs, Simon J. Hall |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
BMI body mass index Urology 030232 urology & nephrology Tumour size Active surveillance Logistic regression AS active surveillance 03 medical and health sciences Prostate cancer 0302 clinical medicine Text mining RALP robot-assisted laparoscopic prostatectomy Biopsy medicine Gleason medicine.diagnostic_test business.industry ASA American Society of Anesthesiologists Magnetic resonance imaging medicine.disease Institutional review board 030220 oncology & carcinogenesis Laparoscopic Prostatectomy Original Article Radiology business Body mass index MRI |
| Zdroj: | Arab Journal of Urology |
| ISSN: | 2090-598X |
| DOI: | 10.1016/j.aju.2016.09.003 |
| Popis: | Objective To investigate whether tumours at threshold values for detection on magnetic resonance imaging (MRI) represent clinically significant tumours or not, and therefore the utility of MRI in active surveillance (AS) protocols. Patients and methods A retrospective analysis of a single institution database was performed after Institutional Review Board approval. Between 2010 and 2013, 1633 patients underwent robot-assisted laparoscopic prostatectomy (RALP) at a single institution by a single surgeon. Of these, 1361 had complete clinical data and were included in analysis. Multivariate logistic regression was used to assess histopathological grade compared to tumour size whilst controlling for biopsy Gleason score, prostate-specific antigen level, body mass index, race, and age. Results Of 120 tumours 3 + 4) at RALP compared to larger tumours (3.3% vs 25.1%, P |
| Databáze: | OpenAIRE |
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