Score reproducibility and reliability in differentiating small bowel subepithelial masses from innocent bulges

Autor: Martina Sciberras, Kelly Conti, Luca Elli, Lucia Scaramella, Maria Elena Riccioni, Clelia Marmo, Sergio Cadoni, Mark McAlindon, Reena Sidhu, Fintan O’hara, Deirdre McNamara, Emanuele Rondonotti, Stefania Piccirelli, Cristiano Spada, Mauro Bruno, Martin Keuchel, Peter Baltes, Neville Calleja, Pablo Cortegoso Valdivia, Gian Luigi de’Angelis, Reuma Margalit-Yehuda, Anastasios Koulaouzidis, Xavier Dray, Pierre Ellul
Rok vydání: 2022
Předmět:
Zdroj: Digestive and Liver Disease. 54:1403-1409
ISSN: 1590-8658
DOI: 10.1016/j.dld.2022.06.027
Popis: The primary aim of this study was to assess the reliability, intra- and inter-observer variation of the SPICE, Mucosal protrusion angle (MPA) and SHYUNG scores in differentiating a subepithelial mass (SEM) from a bulge.This retrospective multicentre study analysed the 3 scores, radiological studies, enteroscopy and/or surgical findings.100 patients with a potential SEM (mean age 57.6years) were recruited with 75 patients having pathology. In patients with a SEM the mean SPICE score was 2.04 (95% CI 1.82-2.26) as compared to 1.16 (95% CI 0.81-1.51) without any pathology (AUC 0.74, p0.001), with a fair intra-observer agreement (Kappa 0.3, p0.001) and slight inter-observer agreement (Kappa 0.14, p0.05). SPICE had a 37.3% sensitivity and 92.0% specificity in distinguishing between a SEM and bulge, whereas MPA90˚ had 58.7% and 76.0% respectively, with poor intra-observer(p = 0.05) and interobserver agreement (p = 0.64). The SHYUNG demonstrated a moderate intra-observer (Kappa 0.44, p0.001) and slight inter-observer reliability (Kappa 0.18, p0.001). The sensitivity of an elevated SHYUNG score (≥4) in identifying a SEM was 18.7% with a specificity of 92.0% (AUC 0.71, p = 0.002).Though these scores are easy to use, they have, at best, slight to moderate intra and inter-observer agreement. Their overall diagnostic performances are limited.
Databáze: OpenAIRE