Oestrus control in bitches with proligestone, a new progestational steroid

Autor:	J. L. Os, E. P. Oldenkamp
Rok vydání:	1978
Předmět:	Gynecology Estrous cycle medicine.medical_specialty Dose business.industry Proligestone Pyometra medicine.disease chemistry.chemical_compound Dogs Estrus chemistry Pregnancy medicine Animals Female Small Animals business Previously treated Progesterone Cystic hyperplasia After treatment
Zdroj:	Journal of Small Animal Practice. 19:521-529
ISSN:	1748-5827 0022-4510
DOI:	10.1111/j.1748-5827.1978.tb05534.x
Popis:	A study of oestrus control in bitches with a new type of progestagen, proligestone, in six Dutch and three UK practices is reported. The product was given subcutaneously, regardless of the stage of the sexual cycle and of the usual contraindications for progestagens. A 97% efficacy was obtained with dosages varying from 20–33 mg/kg for the smallest animals to 10–13 mg/kg for the largest animals, when the first treatment was given in anoestrus with repeated treatments after 3 months, 4 months and thereafter every 5 months. Following treatment in pro–oestrus, heat symptoms disappeared in 96% of the animals within 5 days. By retreatment after 3 months, oestrus prevention could be maintained in 97% of these cases. Where the animals had been treated only with proligestone (1608 treatments in 776 bitches) there were five cases of the cystic hyperplasia pyometra complex; none of these occurred after treatment in pro–oestrus. Of the animals previously treated with other progestagens for oestrus control (814 treatments in 307 bitches) there were 11 cases. Forty–one out of 46 bitches which had a history of reproductive disorders did not show signs again. Other side–effects were also negligible (
Databáze:	OpenAIRE
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