Interaction of intravenous methylprednisolone with oral cyclosporin
| Autor: | C. S. Ubhi, Geoffrey R. Giles, Linda Woodhouse |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Radioimmunoassay Administration Oral Cyclosporins Methylprednisolone medicine Humans Rejection (Psychology) Drug Interactions Kidney transplantation Chromatography High Pressure Liquid Transplantation Kidney business.industry Drug interaction medicine.disease Kidney Transplantation Surgery medicine.anatomical_structure Nephrology Anesthesia Injections Intravenous Corticosteroid business medicine.drug |
| Zdroj: | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 5(5) |
| ISSN: | 0931-0509 |
| Popis: | The plasma cyclosporin values during 17 consecutive rejection episodes in 13 renal allograft recipients have been monitored by high-performance liquid chromatography and radioimmunoassay. In response to anti-rejection therapy with intravenous methylprednisolone, there was a significant increase of greater than 100 ng/ml on only three occasions. We suggest that elevated cyclosporin values during rejection episodes should not be dismissed as the result of steroid therapy and that the original diagnosis must be reviewed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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