The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties
| Autor: | Ertuğrul Emre Güntürk, Hasan Akkaya |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
lcsh:Diseases of the circulatory (Cardiovascular) system
medicine.medical_specialty Coronary slow flow 030204 cardiovascular system & hematology Positive correlation 03 medical and health sciences 0302 clinical medicine Internal medicine medicine carotid-femoral pulse wave velocity 030212 general & internal medicine Pulse wave velocity aortic elastic properties business.industry Slow-Flow Phenomenon Mean age Gold standard (test) medicine.disease Coronary arteries arterial stiffness medicine.anatomical_structure lcsh:RC666-701 Cardiology Arterial stiffness business TIMI Research Paper |
| Zdroj: | JRSM Cardiovascular Disease, Vol 9 (2020) JRSM Cardiovascular Disease |
| ISSN: | 2048-0040 |
| DOI: | 10.1177/2048004020973094 |
| Popis: | Introduction In this study, we aimed to investigate the relationship between coronary slow flow (CSF) and carotid-femoral pulse wave velocity (CFPWV). Methods 78 (27 women, mean age 43.95 ± 7.28) patients with CSF, and 70 (22 women, mean age 44.34 ± 7.08) healthy individuals were included in the study. Arterial stiffness measurement was performed to both groups via CFPWV, which is considered the gold standard. Aortic elastic properties (ASI-β and aortic distensibility) were evaluated in both groups. Results The CSF group had significantly higher CFPWV and aortic distensibility values and significantly lower ASI-β values compared to the control group. There was a positive correlation between TIMI frame count (TFC) obtained in all coronary arteries and CFPWV and aortic distensibility, and a negative correlation between TFC and ASI-β. It was determined that CFPWV predicted CSF with 97% specificity and 98% sensitivity at a 7.68 cut-off value (ROC area = 994, p Conclusion Arterial stiffness increases in CSF patients, suggesting that CSF is a systemic pathology rather than a local disease and that a systemic cause such as atherosclerosis plays a role in etiology. |
| Databáze: | OpenAIRE |
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