Neurocognitive and neurobehavioral disabilities in Epilepsy with Electrical Status Epilepticus in slow sleep (ESES) and related syndromes
Autor: | Sarbani Raha, Vrajesh Udani, Urvashi Shah |
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Rok vydání: | 2012 |
Předmět: |
Male
Sleep Wake Disorders Pediatrics medicine.medical_specialty Clobazam Behavioral Symptoms Status epilepticus Neuropsychological Tests Electroencephalography Behavioral Neuroscience Epilepsy Status Epilepticus medicine Humans Child Retrospective Studies Psychiatric Status Rating Scales medicine.diagnostic_test Neuropsychology Spike-and-wave medicine.disease Neurology Child Preschool Anesthesia Anticonvulsants Female Neurology (clinical) Levetiracetam medicine.symptom Cognition Disorders Sleep Psychology Neurocognitive Follow-Up Studies medicine.drug |
Zdroj: | Epilepsy & Behavior. 25:381-385 |
ISSN: | 1525-5050 |
DOI: | 10.1016/j.yebeh.2012.08.028 |
Popis: | Aim The aims of this study were to assess the cognitive and behavioral problems of patients with Epilepsy with Electrical Status Epilepticus in slow sleep (ESES) and related syndromes and to review their EEG (electroencephalography) findings and treatment options. Results Fourteen patients with ESES were evaluated and treated in 2010. Nine children had continuous spike and wave during slow-wave sleep (CSWS)/ESES syndrome, 3 had Atypical BECTS (benign epilepsy with centrotemporal spikes), 1 had Opercular syndrome, and 1 had Landau–Kleffner syndrome. The duration of ESES ranged from 6 to 52 months. Eleven (91%) children had behavioral issues, most prominent being hyperactivity. Seven of the 13 children (53%) showed evidence of borderline to moderate cognitive impairment. A total of 28 EEG findings of ESES were analyzed for SWI (spike‐wave index). Antiepileptic drugs received by the patients included valproate, clobazam, levetiracetam, and others. Eleven patients had been treated with oral steroids and it was found to be efficacious in seven (63%). Conclusion Disabilities caused by ESES affect multiple domains. Patients with an SWI > 50% should be followed up frequently with neuropsychological assessments. Steroids appear to be effective, although there is a need to standardize the dose and duration of treatment. |
Databáze: | OpenAIRE |
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