Oxidative stress and male infertility: a cross sectional study
| Autor: | Nida Zahid, Hemaila Tariq, Mussarat Ashraf, Masnoon Akhter, Rehana Rehman, Sofia Amjad |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male 0301 basic medicine Infertility Epinephrine Hydrocortisone media_common.quotation_subject Physiology Fertility Antioxidants Male infertility 03 medical and health sciences Follicle-stimulating hormone 0302 clinical medicine Humans Medicine Pakistan Infertility Male Testosterone media_common chemistry.chemical_classification Glutathione Peroxidase Superoxide Dismutase business.industry Glutathione peroxidase General Medicine Middle Aged medicine.disease Oxidative Stress Cross-Sectional Studies Reproductive Health 030104 developmental biology chemistry Case-Control Studies 030220 oncology & carcinogenesis business Luteinizing hormone Gonadal Hormones Stress Psychological Hormone |
| Zdroj: | Journal of the Pakistan Medical Association. :1 |
| ISSN: | 0030-9982 |
| DOI: | 10.5455/jpma.12992 |
| Popis: | OBJECTIVE To compare stress markers and antioxidants in fertile and infertile males, and to explore their effects on reproductive hormones and fertility. METHODS The cross-sectional case-control study was conducted from July 2017 to July 2018 at the Islamabad Clinic Serving Infertile Couples, Islamabad, Pakistan, and comprised male subjects aged 25-55 years. Infertile subjects were the cases, while healthy fertile males acted as the controls. Stress hormones cortisol and adrenaline and antioxidants glutathione peroxidase and superoxide dismutase were measured using enzyme-linked immunosorbent assay. Data was analysed using SPSS 22. RESULTS Of the 376 subjects, 241(64%) were cases and 135(36%) were controls. Median cortisol, adrenaline, superoxide dismutase and glutathione levels were significantly higher among the cases compared to te controls (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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