Seroepidemiology of Measles, Mumps, Rubella and Varicella in Italian Female School Workers: A Cross-Sectional Study
| Autor: | Marcello Campagna, Igor Portoghese, Jacopo Fostinelli, Luigi Isaia Lecca, Nicola Frau, Ilaria Pilia, Laura Portas, Federico Meloni, Giuseppe De Palma, Emma Sala |
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| Rok vydání: | 2021 |
| Předmět: |
Cross-sectional study
Immunology Measles Rubella Article Workplace health surveillance protective immunity Public health surveillance Environmental health Drug Discovery medicine Seroprevalence vaccine-preventable disease Pharmacology (medical) Pharmacology seroprevalence business.industry medicine.disease public health surveillance early childhood teacher Infectious Diseases Cohort Medicine Early childhood teacher Protective immunity School teacher Vaccine-preventable disease Risk assessment business school teacher |
| Zdroj: | Vaccines Volume 9 Issue 10 Vaccines, Vol 9, Iss 1191, p 1191 (2021) |
| ISSN: | 2076-393X |
| DOI: | 10.3390/vaccines9101191 |
| Popis: | Background: Determining the proportion of susceptible workers can represent a first step to the biological risk assessment related to measles, mumps, rubella and varicella exposure. This study aimed to assess the immunity against measles, mumps, rubella and varicella viruses in a cohort of female school workers. Methods: A cross-sectional seroepidemiological study in a sample of 263 school workers undergoing routine annual workplace health surveillance program was conducted. As part of the health surveillance program, serum samples were collected and tested for measles, mumps, rubella and varicella IgG antibodies. Results: Overall seropositivity was 90.5%, 85.2%, 94.7% and 97.3% for measles, mumps, rubella and varicella, respectively. In relation to mumps occupation-specific seropositivity, a statistically significant difference was observed, showing the lowest prevalence of protected individuals in other occupation groups. Moreover, in relation to rubella, school workers born in Centre Italy had the lowest seropositivity of protective antibodies and the difference between groups was statistically significant. Measles and rubella seropositivity showed a significant decrease after 2015. Conclusions: This study showed a relevant proportion of school workers susceptible to the aforementioned diseases. These results highlighted the need for proper health surveillance and immunological controls in school workers, especially for females, and provided useful insights to policymakers to select effective strategies aimed at containing the risk of vaccine-preventable diseases at schools. |
| Databáze: | OpenAIRE |
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