The adulterated XANAX pill: a fatal intoxication with etizolam and caffeine
| Autor: | D. Rentsch, V. Kolbe, Andreas Büttner, D. Boy, B. Schmidt, R. Kegler |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.drug_class
Poison control Case Report Pharmacology Drug abuse 01 natural sciences Anxiolytic Pathology and Forensic Medicine Hypnotic 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Caffeine medicine 030216 legal & forensic medicine Etizolam Benzodiazepine business.industry 010401 analytical chemistry 0104 chemical sciences Alprazolam chemistry Sedative business Adulterated drugs Fatal intoxication medicine.drug |
| Zdroj: | International Journal of Legal Medicine |
| ISSN: | 1437-1596 0937-9827 |
| DOI: | 10.1007/s00414-020-02352-7 |
| Popis: | A 49-year old man was found dead at home next to a glass containing a dried, white, crystalline substance and near a bag containing pills with the imprint XANAX, the trade name of alprazolam. A comprehensive screening of material collected during the autopsy revealed the presence of etizolam and caffeine in lethal concentrations (0.77 μg/mL and 190 μg/mL) but no trace of alprazolam. Benzodiazepine analogue etizolam is rarely prescribed in Germany, and as a result there are not many reports about fatal cases. It has anxiolytic, hypnotic, sedative and muscle-relaxant properties and is used for the short-term treatment of anxiety and panic attacks. The purine alkaloid caffeine, conversely, is the most widely used central nervous system stimulant. The following report outlines potentially the first reported case of a lethal combination of the downer etizolam and the upper caffeine in medical literature. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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