Reduced anterior cingulate activation in aggressive children and adolescents during affective stimulation: Association with temperament traits
| Autor: | Klaus Schmeck, Andreas Kleinschmidt, Christina Stadler, Fritz Poustka, Philipp Sterzer, Annette Krebs |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Male
Cingulate cortex Adolescent media_common.quotation_subject Poison control Gyrus Cinguli Developmental psychology Reaction Time medicine Humans Child Social Behavior Temperament Biological Psychiatry Anterior cingulate cortex International Affective Picture System media_common Novelty seeking medicine.disease Aggression Affect Psychiatry and Mental health Diffusion Magnetic Resonance Imaging medicine.anatomical_structure Conduct disorder Female Temperament and Character Inventory Psychology |
| Zdroj: | Journal of Psychiatric Research. 41:410-417 |
| ISSN: | 0022-3956 |
| DOI: | 10.1016/j.jpsychires.2006.01.006 |
| Popis: | Objective The risk for conduct disorder (CD) is markedly increased in children with specific temperament dimensions. Here, we investigated whether adverse temperament factors might contribute to an impairment in neural mechanisms underlying the regulation of aggressive behaviour. Method Functional magnetic resonance imaging was performed in 13 male adolescents with CD aged 9 to 14 years and in 14 healthy age and sex-matched control subjects at 1.5 T. During scanning, subjects looked at pictures from the International Affective Picture System with neutral or strong negative emotional valence. Temperament was assessed using the German version of the Junior Temperament and Character Inventory. In addition, behavioural control strategies (Wisconsin Card Sorting, Four Pack Card Playing Task) and sociomoral reasoning (Sociomoral Reflection Measure Short Form) were tested to behaviourally characterise the study groups. Results When comparing CD patients with healthy controls, we found reduced activation in the right anterior cingulate cortex (ACC) in response to negative affective pictures. The temperament dimension ‘novelty seeking’ was a significant predictor for ACC responsiveness to affective pictures as revealed by a stepwise multiple regression analysis (β = − 0.53, p |
| Databáze: | OpenAIRE |
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